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  5. Self-assembled micelles for enhancing the oral bioavailability of 9-nitrocamptothecin via Soluplus(R

Self-assembled micelles for enhancing the oral bioavailability of 9-nitrocamptothecin via Soluplus(R

来源 :The 6th International Conference on Nanoscience and Technolo | 被引量 : 0次 | 上传用户：yx2207
【摘 要】
：
Our study aimed to develop an amorphous 9-nitrocamptothecin solid dispersion(9-NC-SD)using polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer(Soluplus(R))for improving its ora
【作 者】
：
Xianghong Lian Tao Gong Yao Fu 
【机 构】
：
Sichuan Univeristy,China
【出 处】
：
The 6th International Conference on Nanoscience and Technolo
【发表日期】
：
2015年5期
【关键词】
：
9-nitrocamptothecin Soluplus(R) micelle solid dispersion Oral bioavailability 
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　　Our study aimed to develop an amorphous 9-nitrocamptothecin solid dispersion(9-NC-SD)using polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer(Soluplus(R))for improving its oral bioavailability and antitumor efficacy in vivo.
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