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  5. N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Co

N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Co

来源 :第八届中国蛋白质组学大会 | 被引量 : 0次 | 上传用户：zi198
【摘 要】
：
The dysregulation of the cancer cell secretome is known to play key roles in tumor transformation and progression.The majority of proteins in the secretome are
【作 者】
：
Xianyu Li Jing Jiang Wantao Ying Xiaohong Qian 
【机 构】
：
TheCollegeofLifeScienceandBio-engineering,BeijingUniversityofTechnology,Beijing,100022,China;StateKe
【出 处】
：
第八届中国蛋白质组学大会
【发表日期】
：
2013年9期
【关键词】
：
Secretome Hepatocellular carcinoma metastasis N-glycoproteins Label-free quantif 
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The dysregulation of the cancer cell secretome is known to play key roles in tumor transformation and progression.The majority of proteins in the secretome are secretory proteins and membrane-released proteins that are glycosylated1.Until recently,few studies have explored protein N-glycosylation changes in the secretome.Here,the N-glycoproteins in the secretome of two human hepatocellular carcinoma (HCC) cell lines with low (MHCC97L) or high (HCCLM3) metastatic potential were investigated.
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