寻常性鱼鳞病(Ichthyosis Vulgaris,Ⅳ)是遗传性皮肤病的一种常见类型,国际上报道其发病率在1:250至1:5300之间,中国人群发病率为0.23%。寻常性鱼鳞病通常在出生后一年内开始起病。其临床特征包括皮肤干燥,病人的四肢伸侧外表皮产生白色的鳞屑,躯干部也偶有出现,还包括掌跖线状皲裂和掌纹加深,遗传性过敏症和不耐热性。寻常性鱼鳞病遗传方式复杂,以常染色体显性遗传多见,存在遗传异质
Dnmt1 and Dnmt3a are important DNA methyltransferases that are expressed in postmitotic neurons.Our previous studies showed that conditional double knock-ou
Nesfatin-1,a newly discovered satiety molecule which reduces feeding behavior,has been recognized as a unique regulatory neuropeptide with its multiple role
Cerebellar cortex receives sensory information from climbing fiber and mossy fiber-granule cell pathways,and generates motor-related outputs according to in
目前，百合(Lilium hybridum）种球的培育有珠芽培养法、小鳞茎培育法、鳞片扦插培育法和种子培育法等。但普遍存在种球退化、繁殖系数低、造成栽培效果较差等问题。另外杂交育种
Depression is one of the most common mood disorders,its unclear etiology pathogenesis is complex and involves many hypothesis.The current clinical applicati
Background:Microglial activation contributes to neuroinflammation and neuronal damages in neurodegenerative disorders including Alzheimers and Parkinsons di
Hydrogen sulfide (H2S),along with NO and CO,considered to be the third endogenous gaseous neuromodulator,also serves as an important neuroprotective agent.H
目的 探讨热疗降低胶质瘤侵袭性的作用与细胞间隙连接通讯(gap junctional intercellular communication,GJIC)的关系.方法 热疗处理C6胶质瘤细胞后,免疫组织化学法和Wes
Extensive research has shown that the aggregation and toxicity of amyloid -beta protein (A β) are closely related to the cognitive deficits in Alzheimers d