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5. Design and synthesis of ebsulfur derivatives as potential inhibitors of metallo-β-lactamase NDM-1

Design and synthesis of ebsulfur derivatives as potential inhibitors of metallo-β-lactamase NDM-1

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：jerryfong

【摘 要】

：

The drug-resistant bacteria have been a serious threat to the clinical treatment.These bacteria hydrolyze almost all β-lactam antibiotics by expressing the metallo-β-lactamses(MβLs).

【作 者】

：

Jianpeng Su Kewu Yang 

【机 构】

：

Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education,Colle

【出 处】

：

中国化学会第十届全国化学生物学学术会议

【发表日期】

：

2017年10期

【关键词】

：

Metallo-β-lactamses NDM-1 Ebsulfur Inhibitor 

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　　The drug-resistant bacteria have been a serious threat to the clinical treatment.These bacteria hydrolyze almost all β-lactam antibiotics by expressing the metallo-β-lactamses(MβLs).

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