Breast Cancer Susceptibility Loci Identification by Meta-analysis

来源 :(BITs 3rd Annual World Cancer Congress-2010, Breast Cancer C | 被引量 : 0次 | 上传用户:jrelt
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  A number of genetic polymorphisms have widely been investigated in population studies for their effects on breast cancer risk, but the association results are inconsistent.Meta-analysis is a useful tool to increase the statistical power to detect gene-disease associations and may provide a summary estimation in detecting and addressing potential inconsistency among the combined datasets.Our group recently carried out meta-analyses on common polymorphisms of TP53 (tumor protein p53) and CYP17 (cytochrome P450 17a hydroxylase) in association with breast cancer risk.
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