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As a coarse-gained model, a super-thin elastic rod subjected to interfacial interactions is used to investigate thecondensation of DNA in intracellular solution. The interfacial traction between the rod and the solution environment isdetermined in terms of the Young-Laplace equation. The Kirchhoff’s theory of elastic rod is used to analyze theequilibrium configuration of a DNA segment under the action of the interfacial traction. The influences of the interfacialenergy factor and bending stiffness on the toroidal spool formation of the DNA segment are discussed. The results showthat the condensation of DNA is mainly determined by competition between the interfacial energy and elastic strainenergy of the DNA itself, and the interfacial traction is one of forces that drive DNA condensation.