Asymmetric hydroxylation of β-keto esters by phase-transfer catalysis using chiral quaternary ammoni

来源 :The 5th Sino-US joint Conference of Chemical Engineering(第五届 | 被引量 : 0次 | 上传用户:airingyuan
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  The catalytic enantioselective hydroxylation promoted by quatemary ammonium salt from cinchonine as a phase-transfer catalyst is described.Treatment of 2-tert-butoxycarbonyl-1-indanone, a kind of β-keto esters, with cumyl hydroperoxide as the oxygen source under mild reaction condition afforded the corresponding a-oxidation of β-keto ester.
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