Synthesis of 5-Methylene Pyrrolone Derivatives for Cysteine Bioconjugation

来源 :中国化学会第十届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：cuileidan

【摘要】

：

　　Cysteine is especially attractive for site-specific chemical modification owing to its high nucleophilicity at physiological conditions and relatively low n

【作者】

：

GuoceAn Yingqian Zhang Chuanzheng Zhou

【机构】

：

StateKeyLaboratoryofElemento-OrganicChemistryandDepartmentofChemicalBiology,CollegeofChemistry,Nanka

【出处】

：

中国化学会第十届全国化学生物学学术会议

【发表日期】

：

2017年9期

【关键词】

：

Bioconjugation 5-methylene pyrrolone Cysteine

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　　Cysteine is especially attractive for site-specific chemical modification owing to its high nucleophilicity at physiological conditions and relatively low natural abundance.

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Synthesis of 5-Methylene Pyrrolone Derivatives for Cysteine Bioconjugation

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