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Cu isotopes (e.g.Cu-64 and Cu-67) increasingly find use in nuclear medicine.Accordingly fast,reliable and easily automatable methods for the production of these isotopes are of great interest.A Cu selective extraction chromatograghic resin (CU Resin,Triskem International) developed for the fast and selective separation of Cu was characterized.Based on the obtained results,a method for the separation of Cu,and its purification from irradiated Ni or Zn targets was developed and tested on simulated Ni and Zn targets,and on an irradiated natural Ni target.Cu yields and decontamination factors for potential interferences have been determined for the developed method.It could be shown that the CU resin has high selectivity over the tested interferences and that Cu can be recovered with high yield and purity in a small volume of 8M HCl within few minutes separation time.A method for the conversion of the Cu elute to lower acid concentrations / higher pH values has equally been developed.