Osteoporosis is the bone disease that is associated with bone mass loss or the breakdown of the bone matrix which leads to an increased risk in bone fracture.Osteoporosis is not only a bone disease in humans but also occurs in animals, particularly laying birds like chicken that use a substantial amount of calcium to make the egg shell.A major amount of the calcium used for egg shell formation is intestinal calcium obtained directly from the diet.However, as laying chicken grow older, their ability to absorb calcium from the diet diminishes but their calcium requirement for egg shell formation remains the same.Additional calcium is obtained from the bones by bone resorption through increased hydrogen ion concentration around the bone joints, a process that ultimately results in osteoporosis.